Sandimmun Neoral Indications/Uses

Transplantation: Solid Organ Transplantation: Prevention of graft rejection following kidney, liver, heart, combined heart-lung, lung or pancreas allogeneic transplantations. Treatment of transplant rejection in patients previously receiving other immunosuppressive agents.
Bone Marrow Transplantation: Prevention of graft rejection following bone marrow transplantation. Prevention or treatment of graft-versus-host disease (GVHD).
Nontransplantation: Endogenous Uveitis: Active sight-threatening intermediate or posterior uveitis of noninfectious etiology where conventional therapy fails or causes unacceptable side effects. Behcet uveitis with repeated inflammatory attacks involving the retina in patients 7-70 years with normal kidney function.
Nephrotic Syndrome: Steroid-dependent and -resistant nephrotic syndrome in adults and children, due to glomerular diseases eg, minimal change nephropathy, focal and segmental glomerulosclerosis or membranous glomerulonephritis.
Sandimmun Neoral can be used to induce remissions and to maintain them. It can also be used to maintain steroid-induced remission, allowing withdrawal of steroids.
Rheumatoid Arthritis: Treatment of severe, active rheumatoid arthritis in whom classical slow-acting antirheumatic agents are inappropriate or ineffective.
Psoriasis: Treatment of severe psoriasis in patients in whom conventional therapy is ineffective or inappropriate.